Substrate: IL-4R alpha (Cytokin receptor)
Seq-ID: P16382 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cytokine receptor activity plasma membrane,
extracellular region,
integral to membrane		 negative regulation of T-helper 1 cell differentiation,
positive regulation of T-helper 2 cell differentiation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 165 YKDLISMVNISREDNPAEFIV - 19144319
HTP
1.00
 - FN3
0.06
 - low
Y 500 VPLVLADNPAYRSFSDCCSPA - 14557412
LTP
1.00
 - -
0.40
 - low

Substrate: IL-4R alpha (Cytokin receptor)
Seq-ID: P24394 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
MINT-63292   ARI2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
receptor signaling protein activity,
interleukin-4 receptor activity		 extracellular region,
integral to plasma membrane		 immune response
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
Y 497 TPLVIAGNPAYRSFSNSLSQS - 9545332
LTP
1.00
 FRS2 PTB;
IRS1 PTB;
SHC1 SH2		 -
0.47
 - medium
Y 497 TPLVIAGNPAYRSFSNSLSQS - 9697832
LTP
1.00
 FRS2 PTB;
IRS1 PTB;
SHC1 SH2		 -
0.47
 - medium
Y 575 AAPVSAPTSGYQEFVHAVEQG - 10358772
LTP
1.00
 PTPN6 SH2;
STAT6 SH2		 -
0.58
 - medium
Y 603 VGLGPPGEAGYKAFSSLLASS - 10358772
LTP
1.00
 STAT6 SH2 -
0.47
 - medium
Y 603 VGLGPPGEAGYKAFSSLLASS - 9712048
LTP
1.00
 STAT6 SH2 -
0.47
 - medium
Y 631 GFGASSGEEGYKPFQDLIPGC - 10358772
LTP
1.00
 STAT6 SH2 -
0.52
 - medium
Y 713 LVDSLGSGIVYSALTCHLCGH - 9670964
LTP
1.00
 INPP5D SH2;
PTPN11 SH2;
PTPN6 SH2;
SHC1 SH2		 -
0.17
 - medium

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